AntiViral Research Center In the Department of Medicine
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Current Studies

The AVRC HQ is actively recruiting for the following studies:

 

HIV

1. PERTURB: The Perturb study will study how routine vaccinations affect the HIV reservoir and what these changes might mean for future cure treatment studies.

What does the study involve?

  • Receive routine annual flu vaccine.
  • Receive routine pneumonia vaccine.
  • 28 weeks of follow up.
  • You may be compensated for participating up to $600.

Eligibility requirements:

  • HIV+ men/women ages 18-50.
  • On HIV therapy for at least 1 year.
  • No allergies to study vaccines.

 

2. ART INTERRUPTION (A5345): This research study aims to find tests that will predict when HIV will be "seen" in blood after temporarily stopping anti-HIV medications (also known as ART) with frequent monitoring.

What does the study involve?

  • You will temporarily stop taking all of your ART about 4 to 9 weeks after you enter the study.
  • During the time you are not taking ART, you will have visits twice a week until the level of HIV in the blood reaches a certain level.
  • You will be compensated for your time and travel for visits.

Eligibility requirements:

  • HIV+ men & women age 18 to 70.
  • On ART for 2 years with undetectable viral load.
  • CD4 count of at least 500 and never below 200.
  • Must be willing to restart ART when instructed or sooner if you prefer.

 

3. DIGITAL ADHERENCE: A novel wireless ingestible sensor system for measurement of medication adherence in HIV-positive men and women that are starting HIV treatment for the first time.

What does the study involve?

  • Nine study visits over a 16 week period with follow up out to 2 years.
  • Participants will receive HIV medication for 16 weeks at no cost.
  • At each study visit, you will be asked to respond to questions about your health and life style, how you are taking HIV medication and how you find using the technology.
  • Compensation provided for your time: $50/study visit.

Eligibility requirements:

  • Age 18 or older.
  • HIV-positive.

 

4. HIV RESERVOIR & HRT: Are you a transgender or gender non-conforming (GNC) person diagnosed with HIV? Do you have plans to start feminizing hormone replacement therapy? We are researching the effects of feminizing hormones on HIV infection.

What does the study involve?

  • Visit our clinic before and after starting feminizing hormone replacement therapy.
  • Provide a sample of blood and genital secretion (optional) at each visit.
  • Each visit should take less than an hour.

Eligibility requirements:

  • HIV+ transgender and GNC persons age 18 year and older.
  • Be ready to start female hormone replacement therapy.
  • On a stable ARV regimen and viral load is undetectable.

 

5. THERAPY FOR CHRONIC PAIN: We want to understand chronic pain in persons aging with HIV and develop treatments to help manage pain.

What does the study involve?

  • Participation in group treatment for 8 weeks.

Eligibility requirements:

  • HIV+ men/women age 50 and older.
  • Pain not associated with cancer for at least 3 months.
  • English-speaking.

 

Sexual Health (for HIV-negative individuals)

1. URBAN NETWORK INTERACTIONS (UNI):

What does the study involve?

This is a social network study involving answering survey questions, getting an HIV test, and recruiting your friends to participate. This study takes place at the AVRC HQ, lasts 1 hour, and has financial compensation.

Eligibility requirements:

  • Men who have sex with men (MSM) and transgender individuals.
  • Age 18 years and older.
  • Live in San Diego.
  • Have a social network of 10+ people who you know well and talk to often.
  • Sexually active.

 

2. TRANSGENDER PrEP: We are looking for transgender and gender non-conforming individuals to join our study for PrEP adherence via text messages.

What does the study involve?

  • Six study visits over a one year period.
  • During each study visit, you would receive PrEP medication and lab tests at no cost, and respond to questions about your sexual health and your experiences on PrEP.
  • Testing for HIV and STDs.
  • Referrals to care and other services (if needed).
  • Compensation provided for your time.

Eligibility requirements:

  • Age 18 or older.
  • Transgender or gender non-conforming.
  • Sexually active and HIV-negative.
  • Have a cell phone that can receive/send text messages.

 

3.THRIVE: This study aims to understand HIV risk for women who have experienced sexual violence or who are sexually active.

What does the study involve?

  • Three study visits over three months, lasting no more than two hours each.
  • Each study visit includes a survey, blood draw, and vaginal exam.
  • Free testing for HIV, STIs, and pregnancy.
  • At home saliva sample collection after each study visit.
  • Referrals to care and other services (if needed).
  • Monetary compensation and transportation provided.

Eligibility requirements:

  • Women age 14 to 45.
  • Live in San Diego.
  • Sexually active within the past week OR have experienced sexual assault in the past week.

       

      To enroll in one of these clinical trials, please call us at (619) 543-8080 and ask for the Screening Coordinator, or email Marvin Hanashiro at mhanashiro@ucsd.edu.

       

      If you would like to be added to the AVRC electronic mailing list, please click here.

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