AntiViral Research Center In the Department of Medicine
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The California Collaborative Treatment Group (CCTG) is a clinical trials consortium of academic institutions and community-based organizations in Southern California.


Since 1986, the CCTG has conducted high-impact, multi-center, investigator-initiated clinical trials focusing on:

  • HIV treatment and management
  • Risk reduction behavioral interventions
  • Pre-Exposure Prophylaxis (PrEP)

The CCTG research team includes clinicians, psychologists, behavioral scientists, biostatisticians, and pharmacology experts.

The CCTG Administrative Core is located at the UCSD AVRC. Collaborators include:

Current funding for the CCTG is provided by the California HIV/AIDS Research Program (CHRP) and backed by the California State Legislature. CHRP fosters outstanding and innovative research that responds to the needs of all people of California, especially those who are often underserved, by accelerating progress in prevention, education, care, treatment, and a cure for HIV/AIDS.

Community members interested in participating in a CCTG study should contact the Screening Coordinator at (619) 543-8080.


Recent Publications and Results

CCTG 600 Jill Blumenthal, MD et al International Workshop on HIV & Women PrEPing for a PrEP Demonstration Project: Understanding Awareness and Perspectives among Women in Southern California
CCTG 596 Kathleen Jacobson, MD et al National HIV Prevention Conference Best Practices for Incentivized Social Network Recruitment for HIV Case Finding
CCTG 595 Martin Hoenigl, MD et al 2017 Conference on Retroviruses and Opportunistic Infections Substance-using MSM on HIV Pre-Exposure Prophylaxis Have Better Adherence
CCTG 595 Michael Dubé, MD et al 18th International Workshop on Co-morbidities and Adverse Drug Reactions in HIV Tenofovir disoproxil fumarate associated with Fanconi syndrome in an HIV uninfected man receiving HIV pre-exposure prophylaxis
CCTG 595 David Moore, PhD et al HIV Research for Prevention Randomized Controlled Trial of Daily Text Messages for Adherence to Pre-Exposure Prophylaxis (PrEP) in Men who have Sex with Men and Transgender Women
CCTG 595 Jill Blumenthal, MD et al International AIDS Society Text messaging responses correlate with tenofovir-disphosphate dried blood spot concentrations among men who have sex with men on pre-exposure prophylaxis
CCTG 595 Joel Milam, PhD et al International AIDS Society Risk compensation among men who have sex with men (MSM) in Southern California following the initiation of pre-exposure prophylaxis (PrEP)
CCTG 595 Sheldon Morris, MD MPH et al National Summit HCV and HIV Diagnosis, Prevention, and Access to Care Comparison of behavioral factors in men who have sex with men who go on HIV pre-exposure prophylaxis by partner status
CCTG 595 Eric Ellorin, et al Infectious Diseases Society of America Barriers to Health Insurance Coverage and Intention to Continue Pre-Exposure Prophylaxis (PrEP) Reported by Men who have Sex with Men (MSM) in a PrEP Demonstration Project
CCTG 593 Katya Corado, MD et al National HIV Prevention Conference Can We Improve HIV Prevention Services?: Understanding the Rationale for Expressed Lack of Interest in PrEP in Recently HIV-tested Individuals
CCTG 592 Sara Gianella, MD et al BMC Infectious Diseases Genital Epstein Barr Virus is associated with Higher Prevalence and Persistence of Anal Human Papilloma Virus in HIV-Infected Men on Antiretroviral Therapy
CCTG 590 Nadejda Beliakova-Bethell, PhD et al Antiviral Research Maraviroc intensification in patients with suppressed HIV viremia has limited effects on CD4+ T cell recovery and gene expression
CCTG 589 Maile Karris, MD et al HIV Clinical Trials
CCTG 589 Maile Karris, MD et al Journal of Acquired Immune Deficiency Syndromes Nucleoside-sparing Regimens with Raltegravir and a Boosted Protease Inhibitor: An Unsettled Issue

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